Dorothy Wynant (Maureen O’Sullivan) is in distress. Her inventor father Clyde (Edward Ellis) has disappeared, after taking $1,000 from his lawyer (Porter Hall) and heading to a secret location, not returning in time for Dorothy’s wedding. Fortunately Nick Charles (William Powell) is in town for the holidays with his wife Nora (Myrna Loy) and their dog Asta (Skippy). Nick is a retired detective who was once hired by Clyde, and after some initial trepidations, Nick is soon on the hunt for the missing man.